Study on synergistic effect of new functionalized Ag nanoparticles for intracellular drug uptake in cancer cells

Yanyan Zhou, Xuemei Wang

Abstract

In this study, we have explored the possibility of the application of the functionalized silver nanoparticles (Ag NPs) as drug carriers allied with anticancer drug daunorubicin (DNR) for efficient cancer chemotherapy. The results demonstrate that Ag NPs can enhance the intracellular drug DNR accumulation concentration in the leukemia K562 cells and thereby increase the killing effect on the leukemia K562 cells.

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Nano Biomedicine and Engineering.

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