Self-Assembly of Complex DNA Nanostructures and Applications

Yonggang Ke *


Department of Biochemical Engineering, Emory University and Georgia Institute of Technology, Atlanta, Georgia 30322, USA.


* Corresponding author. E-mail:


Presented: 1st International Symposium of Shanghai Engineering Research Center for Intelligent Diagnosis and Treatment Instrument (SHIIRC). Shanghai, China, Aug. 7, 2017; Published: Nov. 17, 2017


Citation: Yonggang Ke, Self-Assembly of Complex DNA Nanostructures and Applications. Nano Biomed. Eng., 2017, Special Issue: 281.



A key challenge in nanotechnology is to design and fabricate nanostructures/nanodevices. Such systems can serve as platforms for basic science research (structural biology, molecular biology, for instance) at nanoscale, and for practical applications. Bottom-up structural DNA nanotechnology has attracted significant attentions due to its programmability and its precise control of matter at nanoscale. I will present our recent progress in making massive/complex DNA nanostructures and dynamic DNA devices. DNA nanostructures has also shown increasing capabilities for basic science research, and for practical applications. I will discuss our works on single-molecule biosensors, drug delivery, and fabrication of functional nanoscale materials by using DNA self-assembly.


For details of our lab, visit


Copyright© Yonggang Ke. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Nano Biomedicine and Engineering.

Copyright © Shanghai Jiao Tong University Press