Biomedical Analysis and Manipulation by SPM: From Molecule to Cell

Jie Song *


Institute of Nano Biomedicine and Engineering, Shanghai Engineering Research Centre for Intelligent Diagnosis and Treatment Instrument, Department of Instrument Science and Engineering, School of Electronic Information and Electrical Engineering, Shanghai Jiao Tong University.


* Corresponding author. E-mail:


Presented: 1st International Symposium of Shanghai Engineering Research Center for Intelligent Diagnosis and Treatment Instrument (SHIIRC). Shanghai, China, Aug. 7, 2017; Published: Nov. 17, 2017


Citation: Jie Song, Biomedical Analysis and Manipulation by SPM: From Molecule to Cell. Nano Biomed. Eng., 2017, Special Issue: 283.



Our research interests focus on the development of advanced scanning probe microscopy (SPM) for biomedical analysis and manipulation. In this talk, the detail analysis from molecule to cell will includes: (1) Explore DNA self-assembling nanostructures and its mechanism of the thermodynamics, and develop a new room temperature method for DNA self-assembling; (2) Beside, more recent works will be introduced for single molecular manipulation by DNA nanotechnology; (3) Finally, I will propose our recent efforts to extend the atomic force microscopy’s application on subcellular analysis and manipulation, and focus on detection method of cancer cell biomarkers and biology mechanism of nanodrugs, which would like to provide more supporting for cancer early detection and diagnosis. 


Copyright© Jie Song. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Nano Biomedicine and Engineering.

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