Use of MgCl2 Nanoparticles as Alternative Contrast Media in Magnatic Resonance Imaging Molecular Imaging and Analyzed by Voltammetric Technique

Dunya Ali Mustafa, Haydar Abdulkadeer Taheer Al-Shimmari, Muhammed Mizher Radhi

Abstract

Magnesium chloride compound nanoparticles (MgCl2 NPs) were chosen as alternative contrast medium in magnetic resonance imaging (MRI). The solution of MgCl2 NPs was a good electrochemical property especially in the blood medium. It was found that MgCl2 NPs in blood medium served as an antioxidant reagent because cyclic voltammogram had only one reduction current peak at 0.9 V. Gadolinium compounds were used as a common contrast medium in MRI technique; they had two oxidation current peaks in the blood medium at 0.73 V and 0.23 V. In addition, the gadolinium compounds caused many problems when used as a contrast medium, but they were the only contrast media used for this purpose. It was found that using MgCl2 NPs solution as an alternative contrast medium in rabbits enhanced MR imaging of kidney organ, as compared with that using gadolinium at the same dose.

 

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Nano Biomedicine and Engineering.

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