Facile Green Synthesis of Ag/Agcl Nanocomposite Using Durian Shell Extract and Its Activity Against Methicillin-Resistant Staphylococcus Aureus 

Thi Anh Thu Nguyen, Thi My Thao Nguyen, Thi Thanh Le Trinh, Phung Anh Nguyen, Van Minh Nguyen, Nhat Linh Duong, Trung Dang-Bao, Nguyen Tri

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Abstract

The green synthesis of Ag/AgCl nanocomposite using the durian shell extract was carried out under the sunlight illumination at room temperature, showing the face-centered cubic crystalline structures of both Ag and AgCl with nanosizes in the range of 15–25 nm. The high negative potential value of the Ag/AgCl solution (−21.1 mV) established the high dispersion of Ag/AgCl, long-term stability, and good colloidal nature. The antibacterial activity of Ag/AgCl nanocomposite against methicillin-resistant Staphylococcus aureus (MRSA) bacteria was highly appreciated with average inhibition zone diameter of 12.0 mm, minimum inhibitory concentration of 8.27 mg/L, and minimum bactericidal concentration of 66.1 mg/L. The present work designed a cost-effective, convenient, eco-friendly protocol to synthesize Ag/AgCl nanocomposite and its efficient antibacterial activity against MRSA was evidenced as well.

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Nano Biomedicine and Engineering.

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